Repair Biotechnologies’ REP-0004 mRNA therapy gains FDA orphan drug designation and demonstrates rapid plaque regression in mouse models, potentially revolutionizing cardiovascular care. An mRNA...
First-in-human trial shows Cyclarity’s UDP-003 can safely bind and excrete 7-ketocholesterol, potentially reversing atherosclerosis. Cyclarity Therapeutics’ UDP-003 achieves first safe removal...
UDP-003, a cyclodextrin-based drug, safely reduces 7-ketocholesterol in Phase 1, potentially reversing atherosclerosis instead of just slowing it. A novel drug that removes toxic cholesterol byproduct...
Recent research reveals how mitochondrial decline accelerates cellular senescence in blood vessels, driving conditions like atherosclerosis and blood-brain barrier leakage, with emerging therapies tar...
Recent studies show influenza vaccination lowers heart attack and stroke risks by up to 28% in older adults, emphasizing its role in cardiovascular prevention. Influenza vaccination significantly cuts...
7-ketocholesterol (7KC), an oxidized cholesterol, is linked to cardiovascular and neurodegenerative diseases, with recent AI diagnostics and clinical trials advancing preventive healthcare for aging p...
An analysis of clonal hematopoiesis, a somatic mosaicism in blood cells linked to aging, cancer, and cardiovascular risks, exploring ethical challenges in screening. Recent studies highlight clonal he...
A Nature Communications study shows engineered small extracellular vesicles with platelet proteins restore heart rhythm in rats, offering a safer alternative to pacemakers and gene therapies. Innovati...
Recent studies confirm periodontal disease elevates cardiovascular risk through inflammation, with 2023 findings showing direct bacterial invasion of arteries. This analysis explores mechanisms and pr...
Recent research shows neutrophil extracellular traps accelerate vascular aging by promoting inflammation and endothelial damage, with NET inhibitors offering promising anti-aging therapies for cardiov...
