A new study shows that restoring calcium balance with the antidepressant mianserin extends lifespan in mice, opening avenues for repurposed drugs in aging. A groundbreaking study reveals that disrupte...
Exploring how mild mitochondrial stress through drugs like terbinafine and miglustat extends lifespan, with socioeconomic implications for longevity treatments. New research shows FDA-approved drugs c...
A new aging clock using proteomics and deep learning predicts mortality and chronic diseases, validated by recent UK Biobank studies, promising transformative preventive healthcare. Innovative SASP sc...
A new study on HMGB1’s Box A domain shows it can create DNA gaps, reversing age-related damage in non-human primates with up to 40% proteomic improvement, highlighting potential gene therapy for...
Recent NHANES analyses show that aligning meals with circadian rhythms, especially eating last meals early, reduces epigenetic age acceleration, with benefits varying by age and sex. New research from...
Analyzing recent rapamycin clinical trials for anti-aging, focusing on optimal dosing, safety, and the shift from off-label use to evidence-based protocols in longevity research. New human trials on r...
Exploring the latest breakthroughs in partial reprogramming using OSKM factors for anti-aging, with insights from mouse studies and early clinical trials for eye diseases. Recent studies show partial ...
Senolytic and senomorphic therapies are advancing with compounds like RLS-1496 and α-ESA-me targeting senescent cells. Experts highlight challenges in biomarkers and safety, pushing for personalized ...
Zhang et al. (2026) discovered that α-eleostearic acid and its methyl ester act as novel senolytic agents by inducing ferroptosis in senescent cells, achieving over 80% clearance with minimal toxicit...
Aging research is pivoting from lifespan extension to enhancing healthspan, with innovations like senolytic drugs and digital health tools transforming clinical practices. Recent geroscience advances ...