New CRISPR system selectively kills HPV-positive cancer cells and synergizes with KRAS inhibitors, opening precision medicine avenues. A novel CRISPR system called Cas12a2 can be programmed to destroy...
MIT-led study in Nature Biotechnology uses mRNA-lipid nanoparticles to convert dendritic cells into potent cancer fighters, achieving complete tumor regression in mice. mRNA-loaded nanoparticles repro...
New study shows lifestyle factors have three times greater impact on survival past 80 than genetic predisposition. A landmark study reveals that healthy habits outweigh genes for living longer, even i...
Explore how partial reprogramming using Yamanaka factors reverses epigenetic aging, with recent advances in mice and early clinical trials paving the way for rejuvenation therapies. Partial reprogramm...
A major study reveals aging is a coordinated epigenetic program, not random damage. Single-cell ATAC-seq of 7 million cells shows stereotyped changes across organs, with therapeutic implications. New ...
New research links eusociality to extreme longevity, revealing mechanisms like hyaluronic acid and epigenetic reprogramming that could inspire human anti-aging therapies. Eusocial species live excepti...
New research reveals an inverse relationship between cancer and neurodegenerative diseases, offering evolutionary insights for dual therapies targeting healthy aging. Could the same biological pathway...
A 2023 study in the Journal of Cachexia, Sarcopenia and Muscle finds rapamycin reduces muscle protein synthesis after exercise in older adults, highlighting trade-offs in longevity strategies. Recent ...
Recent studies show that FDA-approved antiretroviral FTC/TAF may slow aging by reducing retrotransposon activity, highlighting a promising gerotherapeutic approach with broad accessibility. Groundbrea...
A new multi-phase clinical trial on rapamycin aims to establish safe dosing for anti-aging, bridging the gap between off-label use and scientific validation in longevity medicine. Recent advancements ...