The 2026 Alzheimer’s clinical trials pipeline shows a strategic shift from amyloid to inflammation and tau targets, with combination therapies and repurposed drugs leading the way. In 2026, the Alzh...
Alzheimer’s Drug Development Revolution: Inflammation and Tau Take Center Stage as Amyloid Era Fades
The 2024 pipeline report reveals a dramatic shift from amyloid to inflammation and tau targets, with repurposed drugs and combination therapies leading a new era of Alzheimer’s treatment. New re...
Recent studies reveal that immune aging, or ‘inflammaging,’ is a modifiable risk factor for neurodegenerative diseases, with new biomarkers and senolytic drugs offering hope for early inte...
The 2025 longevity investment landscape shifts from narrow anti-aging to a full innovation stack, led by cellular reprogramming, brain longevity diagnostics, and platform infrastructure. Investors pou...
Senolytic and senomorphic therapies are advancing with compounds like RLS-1496 and α-ESA-me targeting senescent cells. Experts highlight challenges in biomarkers and safety, pushing for personalized ...
Recent breakthroughs in senolytic and senomorphic therapies, including polyunsaturated lipids inducing ferroptosis, are advancing clinical trials for age-related diseases, with a focus on safety and b...
Recent breakthroughs in epigenetic clocks, particularly DunedinPACE, enhance mortality prediction accuracy by up to 20%, validated by studies like BASE-II, and drive innovations in personalized medici...
Recent studies reveal complement system biomarkers, such as C3 and C4, change with age and correlate with dementia, offering potential for early Alzheimer’s detection and insights into immune sy...
Research shows muscularis macrophages in the gut trigger α-synuclein misfolding in Parkinson’s disease, spreading to the brain via immune pathways, with potential for early intervention through...
A 2023 meta-analysis confirms GrimAge epigenetic age acceleration consistently predicts frailty, enabling early risk assessment and personalized interventions for elderly health. Recent studies show e...