Recent studies reveal that age-related proteasomal decline activates the cGAS-STING pathway through mitochondrial DNA leakage, fueling chronic inflammation linked to Alzheimer’s, with exercise a...
New research reveals APOE ε3 and ε4 variants are implicated in most Alzheimer’s cases, sparking debates on genetic screening, lifestyle changes, and gene therapy in prevention strategies. A gr...
Recent studies reveal that cystathionine γ-lyase (CSE) deficiency accelerates brain aging via reduced hydrogen sulfide, offering new therapeutic avenues for neurodegenerative diseases. Groundbreaking...
This article explores how senotherapeutics target senescent cells in the brain to reduce neuroinflammation and improve cognition, based on recent preclinical studies and emerging clinical trials. Emer...
Recent research shows compounds like P7C3-A20 restore NAD+ levels, reversing Alzheimer’s pathology in mice, with early clinical trials indicating safety and potential efficacy in humans. Breakth...
A 2025 research paper finds that obese individuals with low choline levels face increased Alzheimer’s disease risk due to inflammation and neuronal damage, highlighting dietary interventions. Re...
New research links impaired glymphatic drainage to early cognitive decline, with DTI-ALPS imaging enabling early detection. Lifestyle interventions like sleep and exercise show promise in supporting b...
The Phase 3 failure of semaglutide in Alzheimer’s disease highlights challenges in repurposing GLP-1 agonists, urging a shift towards biomarker-driven and personalized approaches in neurodegener...
Recent evidence shows moderate walking reduces tau buildup and inflammation, slowing Alzheimer’s progression. Epidemiological studies highlight dose-response benefits for accessible preventive h...
